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SPAG5 interacts with CEP55 and exerts oncogenic activities via PI3K/AKT pathway in hepatocellular carcinoma

BACKGROUND: Deregulation of microtubules and centrosome integrity is response for the initiation and progression of human cancers. Sperm-associated antigen 5 (SPAG5) is essential for the spindle apparatus organization and chromosome segregation, but its role in hepatocellular carcinoma (HCC) remains...

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Foilsithe in:Mol Cancer
Main Authors: Yang, Yu-Feng, Zhang, Mei-Fang, Tian, Qiu-Hong, Fu, Jia, Yang, Xia, Zhang, Chris Zhiyi, Yang, Hong
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6081940/
https://ncbi.nlm.nih.gov/pubmed/30089483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-018-0872-3
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