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Detection of cyclooxygenase-2-derived oxygenation products of the endogenous cannabinoid 2-arachidonoylglycerol in mouse brain

Cyclooxygenase-2 (COX-2) catalyzes the formation of prostaglandins, which are involved in immune regulation, vascular function, and synaptic signaling. COX-2 also inactivates the endogenous cannabinoid (eCB) 2-arachidonoylglycerol (2-AG) via oxygenation of its arachidonic acid backbone to form a var...

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Bibliografische gegevens
Gepubliceerd in:ACS Chem Neurosci
Hoofdauteurs: Morgan, Amanda, Kingsley, Phillip J., Mitchener, Michelle M., Altemus, Megan, Patrick, Toni, Gaulden, Andrew, Marnett, Lawrence J., Patel, Sachin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6081739/
https://ncbi.nlm.nih.gov/pubmed/29722963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.7b00499
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