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Monitoring the action of redox-directed cancer therapeutics using a human peroxiredoxin-2-based probe

Redox cancer therapeutics target the increased reliance on intracellular antioxidant systems and enhanced susceptibility to oxidant-induced stress of some cancer cells compared to normal cells. Many of these therapeutics are thought to perturb intracellular levels of the oxidant hydrogen peroxide (H...

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Publicat a:Nat Commun
Autors principals: Langford, Troy F., Huang, Beijing K., Lim, Joseph B., Moon, Sun Jin, Sikes, Hadley D.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6081480/
https://ncbi.nlm.nih.gov/pubmed/30087344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05557-y
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