Serotonin depletion causes valproate-responsive manic-like condition and increased hippocampal neuroplasticity that are reversed by stress

Abnormal hippocampal neural plasticity has been implicated in behavioural abnormalities and complex neuropsychiatric conditions, including bipolar disorder (BD). However, the determinants of this neural alteration remain unknown. This work tests the hypothesis that the neurotransmitter serotonin (5-...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Maddaloni, Giacomo, Migliarini, Sara, Napolitano, Francesco, Giorgi, Andrea, Nazzi, Serena, Biasci, Daniele, De Felice, Alessia, Gritti, Marta, Cavaccini, Anna, Galbusera, Alberto, Franceschi, Sara, Lessi, Francesca, Ferla, Marco La, Aretini, Paolo, Mazzanti, Chiara Maria, Tonini, Raffaella, Gozzi, Alessandro, Usiello, Alessandro, Pasqualetti, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6081464/
https://ncbi.nlm.nih.gov/pubmed/30087403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30291-2
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