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Critical role of CD4(+) T cells and IFNγ signaling in antibody-mediated resistance to Zika virus infection
Protective adaptive immunity to Zika virus (ZIKV) has been mainly attributed to cytotoxic CD8(+) T cells and neutralizing antibodies, while the participation of CD4(+) T cells in resistance has remained largely uncharacterized. Here, we show a neutralizing antibody response, dependent on CD4(+) T ce...
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Publicado no: | Nat Commun |
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Main Authors: | , , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group UK
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6081430/ https://ncbi.nlm.nih.gov/pubmed/30087337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05519-4 |
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