Intestinal regulation of suppression of tumorigenicity 14 (ST14) and serine peptidase inhibitor, Kunitz type -1 (SPINT1) by transcription factor CDX2

The type II membrane-anchored serine protease, matriptase, encoded by suppression of tumorgenicity-14 (ST14) regulates the integrity of the intestinal epithelial barrier in concert with its inhibitor, HAI-1 encoded by serine peptidase inhibitor, Kunitz type -1 (SPINT1). The balance of the protease/i...

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Publicat a:Sci Rep
Autors principals: Danielsen, E. Thomas, Olsen, Anders Krüger, Coskun, Mehmet, Nonboe, Annika W., Larsen, Sylvester, Dahlgaard, Katja, Bennett, Eric Paul, Mitchelmore, Cathy, Vogel, Lotte Katrine, Troelsen, Jesper Thorvald
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6081401/
https://ncbi.nlm.nih.gov/pubmed/30087389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30216-z
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