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Formulation, characterization and evaluation of mRNA-loaded dissolvable polymeric microneedles (RNApatch)
In this paper, we report a proof of concept study on the fabrication, characterization and therapeutic evaluation of in vitro transcribed messenger RNA (mRNA) loaded in a dissolving microneedle patch (RNApatch). We show that low molecular weight polyvinylpyrrolidone (PVP) can directly be used withou...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6081392/ https://ncbi.nlm.nih.gov/pubmed/30087399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30290-3 |
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