Prognostic significance of PIK3CA mutation in stage IIB to IVA cervical cancers treated by concurrent chemoradiotherapy with weekly cisplatin

The standard treatment for locally advanced cervical cancer is cisplatin-based concurrent chemoradiotherapy (CCRT). Although the activated PI3-kinase/Akt pathway is known to be involved in both cisplatin-resistance and radioresistance, to date, only a few studies have reported significant associatio...

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Detalhes bibliográficos
Publicado no:Medicine (Baltimore)
Main Authors: Lachkar, Bouchra, Minaguchi, Takeo, Akiyama, Azusa, Liu, Shuling, Zhang, Shuang, Xu, Chenyang, Shikama, Ayumi, Tasaka, Nobutaka, Sakurai, Manabu, Nakao, Sari, Ochi, Hiroyuki, Yoshikawa, Hiroyuki, Satoh, Toyomi
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer Health 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6081058/
https://ncbi.nlm.nih.gov/pubmed/30075505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000011392
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