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F-Actin nucleated on chromosomes coordinates their capture by microtubules in oocyte meiosis
Capture of each and every chromosome by spindle microtubules is essential to prevent chromosome loss and aneuploidy. In somatic cells, astral microtubules search and capture chromosomes forming lateral attachments to kinetochores. However, this mechanism alone is insufficient in large oocytes. We ha...
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| Udgivet i: | J Cell Biol |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Rockefeller University Press
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6080919/ https://ncbi.nlm.nih.gov/pubmed/29903878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201802080 |
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