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ATP competes with PIP(2) for binding to gelsolin

Gelsolin is a severing and capping protein that targets filamentous actin and regulates filament lengths near plasma membranes, contributing to cell movement and plasma membrane morphology. Gelsolin binds to the plasma membrane via phosphatidylinositol 4,5-bisphosphate (PIP(2)) in a state that canno...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Szatmári, Dávid, Xue, Bo, Kannan, Balakrishnan, Burtnick, Leslie D., Bugyi, Beáta, Nyitrai, Miklós, Robinson, Robert C.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6080781/
https://ncbi.nlm.nih.gov/pubmed/30086165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0201826
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