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In wound repair vimentin mediates the transition of mesenchymal leader cells to a myofibroblast phenotype

Following injury, mesenchymal repair cells are activated to function as leader cells that modulate wound healing. These cells have the potential to differentiate to myofibroblasts, resulting in fibrosis and scarring. The signals underlying these differing pathways are complex and incompletely unders...

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Détails bibliographiques
Publié dans:Mol Biol Cell
Auteurs principaux: Walker, J. L., Bleaken, B. M., Romisher, A. R., Alnwibit, A. A., Menko, A. S.
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6080657/
https://ncbi.nlm.nih.gov/pubmed/29718762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-06-0364
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