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Influence of the KCNQ1 S140G Mutation on Human Ventricular Arrhythmogenesis and Pumping Performance: Simulation Study

The KCNQ1 S140G mutation, which is involved in I(Ks) current, affects atrial fibrillation. However, little is known about its effect on the mechanical behavior of the heart. Therefore, we assessed the influence of the KCNQ1 S140G mutation on ventricular electrophysiological stability and mechanical...

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Pubblicato in:Front Physiol
Autori principali: Jeong, Da Un, Lim, Ki Moo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6080549/
https://ncbi.nlm.nih.gov/pubmed/30108508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.00926
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