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Streptococcus mutans activates the AIM2, NLRP3 and NLRC4 inflammasomes in human THP-1 macrophages

Streptococcus mutans (S. mutans), a major aetiologic agent of dental caries, is involved in systemic diseases, such as bacterial endocarditis, if it enters the bloodstream through temporary bacteraemia. Interleukin (IL)-1β, a proinflammatory cytokine, is related to the host defences against pathogen...

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Bibliografiske detaljer
Udgivet i:Int J Oral Sci
Main Authors: Song, Yuri, Na, Hee Sam, Park, Eunjoo, Park, Mi Hee, Lee, Hyun Ah, Chung, Jin
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6080406/
https://ncbi.nlm.nih.gov/pubmed/30078841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41368-018-0024-z
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