YC-1 activation of human soluble guanylyl cyclase has both heme-dependent and heme-independent components
YC-1 [3-(5′-hydroxymethyl-2′furyl)-1-benzyl indazole] is an allosteric activator of soluble guanylyl cyclase (sGC). YC-1 increases the catalytic rate of the enzyme and sensitizes the enzyme toward its gaseous activators nitric oxide or carbon monoxide. In other studies the administration of YC-1 to...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2001
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC60803/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11687640/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.231486198 |
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