Local Delivery of miR-21 Stabilizes Fibrous Caps in Vulnerable Atherosclerotic Lesions

miRNAs are potential regulators of carotid artery stenosis and concordant vulnerable atherosclerotic plaques. Hence, we analyzed miRNA expression in laser captured micro-dissected fibrous caps of either ruptured or stable plaques (n = 10 each), discovering that miR-21 was significantly downregulated...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Jin, Hong, Li, Daniel Y., Chernogubova, Ekaterina, Sun, Changyan, Busch, Albert, Eken, Suzanne M., Saliba-Gustafsson, Peter, Winter, Hanna, Winski, Greg, Raaz, Uwe, Schellinger, Isabel N., Simon, Nancy, Hegenloh, Renate, Matic, Ljubica Perisic, Jagodic, Maja, Ehrenborg, Ewa, Pelisek, Jaroslav, Eckstein, Hans-Henning, Hedin, Ulf, Backlund, Alexandra, Maegdefessel, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6080193/
https://ncbi.nlm.nih.gov/pubmed/29503197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.01.011
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