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Position within the host intron is critical for efficient processing of box C/D snoRNAs in mammalian cells

In mammalian cells, all small nucleolar RNAs (snoRNAs) that guide rRNA modification are encoded within the introns of host genes. A database analysis of human box C/D snoRNAs revealed conservation of their intronic location, with a preference for 70–80 nt upstream of the 3′ splice site. Transfection...

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Bibliografiske detaljer
Main Authors: Hirose, Tetsuro, Steitz, Joan A.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC60799/
https://ncbi.nlm.nih.gov/pubmed/11606788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.231490998
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