Deficiency in intestinal epithelial O‐GlcNAcylation predisposes to gut inflammation

Post‐translational modifications in intestinal epithelial cells (IECs) allow for precise control in intestinal homeostasis, the breakdown of which may precipitate the pathological damage and inflammation in inflammatory bowel disease. The O‐linked β‐N‐acetylglucosamine (O‐GlcNAc) modification on int...

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Detalhes bibliográficos
Publicado no:EMBO Mol Med
Main Authors: Zhao, Ming, Xiong, Xiwen, Ren, Kaiqun, Xu, Bing, Cheng, Meng, Sahu, Chinmayi, Wu, Kaichun, Nie, Yongzhan, Huang, Zan, Blumberg, Richard S, Han, Xiaonan, Ruan, Hai‐Bin
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6079539/
https://ncbi.nlm.nih.gov/pubmed/29941542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201708736
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