Type M Resistance to Macrolides Is Due to a Two-Gene Efflux Transport System of the ATP-Binding Cassette (ABC) Superfamily

The mef(A) gene was originally identified as the resistance determinant responsible for type M resistance to macrolides, a phenotype frequently found in clinical isolates of Streptococcus pneumoniae and Streptococcus pyogenes. MefA was defined as a secondary transporter of the major facilitator supe...

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Vydáno v:Front Microbiol
Hlavní autoři: Iannelli, Francesco, Santoro, Francesco, Santagati, Maria, Docquier, Jean-Denis, Lazzeri, Elisa, Pastore, Gabiria, Cassone, Marco, Oggioni, Marco R., Rossolini, Gian M., Stefani, Stefania, Pozzi, Gianni
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Microbiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6079230/
https://ncbi.nlm.nih.gov/pubmed/30108557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.01670
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