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Development of an inducible anti-VEGF rAAV gene therapy strategy for the treatment of wet AMD

Vascular endothelial growth factor (VEGF) is a key mediator in the development and progression of choroidal neovascularization (CNV) in patients with wet age-related macular degeneration (AMD). As a consequence, current treatment strategies typically focus on the administration of anti-VEGF agents,...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Reid, Christopher A., Nettesheim, Emily R., Connor, Thomas B., Lipinski, Daniel M.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6079038/
https://ncbi.nlm.nih.gov/pubmed/30082848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29726-7
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