Insights into the structure and dynamics of lysyl oxidase propeptide, a flexible protein with numerous partners

Lysyl oxidase (LOX) catalyzes the oxidative deamination of lysine and hydroxylysine residues in collagens and elastin, which is the first step of the cross-linking of these extracellular matrix proteins. It is secreted as a proenzyme activated by bone morphogenetic protein-1, which releases the LOX...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Vallet, Sylvain D., Miele, Adriana E., Uciechowska-Kaczmarzyk, Urszula, Liwo, Adam, Duclos, Bertrand, Samsonov, Sergey A., Ricard-Blum, Sylvie
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6078952/
https://ncbi.nlm.nih.gov/pubmed/30082873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30190-6
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