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Hypoxia-inducible factor cell non-autonomously regulates C. elegans stress responses and behavior via a nuclear receptor

The HIF (hypoxia-inducible factor) transcription factor is the master regulator of the metazoan response to chronic hypoxia. In addition to promoting adaptations to low oxygen, HIF drives cytoprotective mechanisms in response to stresses and modulates neural circuit function. How most HIF targets ac...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Pender, Corinne L, Horvitz, H Robert
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6078495/
https://ncbi.nlm.nih.gov/pubmed/30010540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.36828
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