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Comparison of biosimilar filgrastim with a reference product: pharmacokinetics, pharmacodynamics, and safety profiles in healthy volunteers
PURPOSE: Filgrastim, a granulocyte-colony stimulating factor, is used to treat patients with neutropenia, including neutropenic fever. Leucostim(®) is a recombinant filgrastim product tested for biosimilarity with its reference product, Neupogen(®). We conducted a comparative clinical trial of the 2...
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| Publicado no: | Drug Des Devel Ther |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6078186/ https://ncbi.nlm.nih.gov/pubmed/30122896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S158277 |
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