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The role of drug profiles as similarity metrics: applications to repurposing, adverse effects detection and drug–drug interactions

Explosion of the availability of big data sources along with the development in computational methods provides a useful framework to study drugs’ actions, such as interactions with pharmacological targets and off-targets. Databases related to protein interactions, adverse effects and genomic profile...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Brief Bioinform
Hauptverfasser: Vilar, Santiago, Hripcsak, George
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6078166/
https://ncbi.nlm.nih.gov/pubmed/27273288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bib/bbw048
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