Detection of identical T cell clones in peritumoral pleural effusion and pneumonitis lesions in a cancer patient during immune-checkpoint blockade

Although immune-related adverse events (irAEs) of treatment with immune-checkpoint inhibitors may be due to cellular immunity mediated by T lymphocytes, their pathogenesis has remained unknown. Here we collected bronchoalveolar lavage fluid (BALF) from a cancer patient with nivolumab-induced pneumon...

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Detalhes bibliográficos
Publicado no:Oncotarget
Principais autores: Tanaka, Kentaro, Yanagihara, Toyoshi, Ikematsu, Yuki, Inoue, Hiroyuki, Ota, Keiichi, Kashiwagi, Eiji, Suzuki, Kunihiro, Hamada, Naoki, Takeuchi, Ario, Tatsugami, Katsunori, Eto, Masatoshi, Ijichi, Kayo, Oda, Yoshinao, Otsubo, Kohei, Yoneshima, Yasuto, Iwama, Eiji, Nakanishi, Yoichi, Okamoto, Isamu
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6078130/
https://ncbi.nlm.nih.gov/pubmed/30093971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25743
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