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N-Terminal Extension and C-Terminal Domains Are Required for ABCB6/HMT-1 Protein Interactions, Function in Cadmium Detoxification, and Localization to the Endosomal-Recycling System in Caenorhabditis elegans

The chronic exposure of humans to toxic metals such as cadmium from food and air causes dysfunction of vital organs, neurodegenerative conditions, and cancer. In this regard, members of the ABCB sub-family of the ATP-binding cassette (ABC) transporter superfamily, ABCB6/HMT-1, are acutely required f...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Kim, Sungjin, Sharma, Anuj K., Vatamaniuk, Olena K.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6077975/
https://ncbi.nlm.nih.gov/pubmed/30104978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.00885
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