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Molecular Docking Analysis of Pyrimethamine Derivatives with Plasmodium falciparum Dihydrofolate Reductase

DHFR from Pf is a known target for malaria. There is a continued effort for the design and development of the potent inhibitor for PfDHFR in the control of malaria. Therefore it is of interest to screen PfDHFR with the derivatives of Pyrimethamine. The results show that the compound CID 10476801 has...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Bioinformation
Hauptverfasser: Singh, Indra Vikram, Mishra, Sanjay
Format: Artigo
Sprache:Inglês
Veröffentlicht: Biomedical Informatics 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6077817/
https://ncbi.nlm.nih.gov/pubmed/30108420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630014232
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