Circulating Dephospho-Uncarboxylated Matrix Gla-Protein Is Associated With Kidney Dysfunction and Arterial Stiffness

BACKGROUND: Large artery stiffening is increased in advanced chronic kidney disease (CKD) but likely develops progressively in earlier stages of CKD. Active matrix Gla-protein (MGP) is a potent vitamin K–dependent inhibitor of vascular calcification. A recent animal model demonstrated intrinsic abno...

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Detalhes bibliográficos
Publicado no:Am J Hypertens
Main Authors: Puzantian, Houry, Akers, Scott R, Oldland, Garrett, Javaid, Khuzaima, Miller, Rachana, Ge, Yueya, Ansari, Bilal, Lee, Jonathan, Suri, Arpita, Hasmath, Zeba, Townsend, Raymond, Chirinos, Julio A
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Original Contributions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6077812/
https://ncbi.nlm.nih.gov/pubmed/29788226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ajh/hpy079
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