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Repair of Chromosome Ends after Telomere Loss in Saccharomyces

Removal of a telomere from yeast chromosome VII in a strain having two copies of this chromosome often results in its loss. Here we show that there are three pathways that can stabilize this broken chromosome: homologous recombination, nonhomologous end joining, and de novo telomere addition. Both i...

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Détails bibliographiques
Auteurs principaux: Mangahas, Jeff L., Alexander, Mary Kate, Sandell, Lisa L., Zakian, Virginia A.
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 2001
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC60777/
https://ncbi.nlm.nih.gov/pubmed/11739802
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