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Maturation of GABAergic Transmission in Cerebellar Purkinje Cells Is Sex Dependent and Altered in the Valproate Model of Autism

Brain development is accompanied by a shift in gamma-aminobutyric acid (GABA) response from depolarizing-excitatory to hyperpolarizing-inhibitory, due to a reduction of intracellular chloride concentration. This sequence is delayed in Autism Spectrum Disorders (ASD). We now report a similar alterati...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Roux, Sébastien, Lohof, Ann, Ben-Ari, Yehezkel, Poulain, Bernard, Bossu, Jean-Louis
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6077203/
https://ncbi.nlm.nih.gov/pubmed/30104962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2018.00232
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