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Self-Crosslinking Lipopeptide/DNA/PEGylated Particles: A New Platform for DNA Vaccination Designed for Assembly in Aqueous Solution

Delivery of plasmids for gene expression in vivo is an inefficient process that requires improvement and optimization to unlock the clinical potential of DNA vaccines. With ease of manufacture and biocompatibility in mind, we explored condensation of DNA in aqueous solution with a self-crosslinking,...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Ho, Joan K., White, Paul J., Pouton, Colin W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6077166/
https://ncbi.nlm.nih.gov/pubmed/30195787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2018.05.025
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