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Self-Crosslinking Lipopeptide/DNA/PEGylated Particles: A New Platform for DNA Vaccination Designed for Assembly in Aqueous Solution
Delivery of plasmids for gene expression in vivo is an inefficient process that requires improvement and optimization to unlock the clinical potential of DNA vaccines. With ease of manufacture and biocompatibility in mind, we explored condensation of DNA in aqueous solution with a self-crosslinking,...
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Publicado no: | Mol Ther Nucleic Acids |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society of Gene & Cell Therapy
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6077166/ https://ncbi.nlm.nih.gov/pubmed/30195787 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2018.05.025 |
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