A Reduction in ADAM17 Expression Is Involved in the Protective Effect of the PPAR-α Activator Fenofibrate on Pressure Overload-Induced Cardiac Hypertrophy

The peroxisome proliferator-activated receptor-α (PPAR-α) agonist fenofibrate ameliorates cardiac hypertrophy; however, its mechanism of action has not been completely determined. Our previous study indicated that a disintegrin and metalloproteinase-17 (ADAM17) is required for angiotensin II-induced...

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Vydáno v:PPAR Res
Hlavní autoři: Zeng, Si-Yu, Lu, Hui-Qin, Yan, Qiu-Jiang, Zou, Jian
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6076894/
https://ncbi.nlm.nih.gov/pubmed/30105051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/7916953
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