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Intranasal rifampicin for Alzheimer's disease prevention
INTRODUCTION: Oral rifampicin has been shown to significantly reduce amyloid β (Aβ) and tau pathologies in mice. However, it shows occasional adverse effects such as liver injury in humans, making its use difficult for a long period. METHODS: To explore safer rifampicin treatment, APP(OSK) mice, a m...
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| Izdano u: | Alzheimers Dement (N Y) |
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| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Elsevier
2018
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6076366/ https://ncbi.nlm.nih.gov/pubmed/30094330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trci.2018.06.012 |
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