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Pre-neoplastic pancreas cells enter a partially mesenchymal state following transient TGF-β exposure
Pancreatic ductal adenocarcinoma (PDAC) is a deadly disease and a major health problem in the United States. While the cytokine TGF-β has been implicated in PDAC development, it can exert both pro- and anti-tumorigenic effects that are highly context dependent and incompletely understood. Using thre...
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| Опубликовано в: : | Oncogene |
|---|---|
| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6076343/ https://ncbi.nlm.nih.gov/pubmed/29713060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0264-6 |
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