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Regulation of miR-181a expression in T cell aging

MicroRNAs have emerged as key regulators in T cell development, activation, and differentiation, with miR-181a having a prominent function. By targeting several signaling pathways, miR-181a is an important rheostat controlling T cell receptor (TCR) activation thresholds in thymic selection as well a...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Ye, Zhongde, Li, Guangjin, Kim, Chulwoo, Hu, Bin, Jadhav, Rohit R., Weyand, Cornelia M., Goronzy, Jörg J.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6076328/
https://ncbi.nlm.nih.gov/pubmed/30076309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05552-3
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