Heterotetrameric annexin A2/S100A10 (A2t) is essential for oncogenic human papillomavirus trafficking and capsid disassembly, and protects virions from lysosomal degradation

Human papillomavirus (HPV) entry into epithelial cells is independent of canonical endocytic pathways. Upon interaction with host cells, HPV establishes infection by traversing through an endocytic pathway that is clathrin- and caveolin-independent, but dependent on the annexin A2/S100A10 heterotetr...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Taylor, Julia R., Fernandez, Daniel J., Thornton, Shantaé M., Skeate, Joseph G., Lühen, Kim P., Da Silva, Diane M., Langen, Ralf, Kast, W. Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6076308/
https://ncbi.nlm.nih.gov/pubmed/30076379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30051-2
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