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Fitting mathematical models of biochemical pathways to steady state perturbation response data without simulating perturbation experiments
Fitting Ordinary Differential Equation (ODE) models of signal transduction networks (STNs) to experimental data is a challenging problem. Computational parameter fitting algorithms simulate a model many times with different sets of parameter values until the simulated STN behaviour match closely wit...
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| Wydane w: | Sci Rep |
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| 1. autor: | |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Publishing Group UK
2018
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6076289/ https://ncbi.nlm.nih.gov/pubmed/30076370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30118-0 |
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