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Reciprocal Perspective for Improved Protein-Protein Interaction Prediction

All protein-protein interaction (PPI) predictors require the determination of an operational decision threshold when differentiating positive PPIs from negatives. Historically, a single global threshold, typically optimized via cross-validation testing, is applied to all protein pairs. However, we h...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Dick, Kevin, Green, James R.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6076239/
https://ncbi.nlm.nih.gov/pubmed/30076341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30044-1
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