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Randomized, Open-Label Phase II Study Evaluating the Efficacy and Safety of Talimogene Laherparepvec in Combination With Ipilimumab Versus Ipilimumab Alone in Patients With Advanced, Unresectable Melanoma
PURPOSE: We evaluated the combination of talimogene laherparepvec plus ipilimumab versus ipilimumab alone in patients with advanced melanoma in a phase II study. To our knowledge, this was the first randomized trial to evaluate addition of an oncolytic virus to a checkpoint inhibitor. METHODS: Patie...
Zapisane w:
| Wydane w: | J Clin Oncol |
|---|---|
| Główni autorzy: | , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society of Clinical Oncology
2018
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6075852/ https://ncbi.nlm.nih.gov/pubmed/28981385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2017.73.7379 |
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