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Rat heart cannot synthesize docosahexaenoic acid from circulating α-linolenic acid because it lacks elongase-2

The extent to which the heart can convert α-linolenic acid (α-LNA, 18:3n-3) to longer chain n-3 PUFAs is not known. Conversion rates can be measured in vivo using radiolabeled α-LNA and a kinetic fatty acid model. [1-(14)C]α-LNA was infused intravenously for 5 min in unanesthetized rats that had bee...

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Bibliografiska uppgifter
I publikationen:J Lipid Res
Huvudupphovsmän: Igarashi, Miki, Ma, Kaizong, Chang, Lisa, Bell, Jane M., Rapoport, Stanley I.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6075821/
https://ncbi.nlm.nih.gov/pubmed/18456640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M800093-JLR200
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