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Phase I trial of UNBS5162, a novel naphthalimide in patients with advanced solid tumors or lymphoma
OBJECTIVES: UNBS5162 is a novel naphthalimide that binds to DNA by intercalation and suppresses CXCL chemokine elaboration. A Phase I study of UNBS5162 was conducted to establish pharmacokinetics (PK), maximum tolerated dose (MTD), dose-limiting toxicity, safety and anti-tumor activity in patients w...
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| izdano v: | Int J Clin Oncol |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6075731/ https://ncbi.nlm.nih.gov/pubmed/23053399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10147-012-0475-8 |
| Oznake: |
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