Intraflagellar transport 88 (IFT88) is crucial for craniofacial development in mice and is a candidate gene for human cleft lip and palate

Ciliopathies are pleiotropic human diseases resulting from defects of the primary cilium, and these patients often have cleft lip and palate. IFT88 is required for the assembly and function of the primary cilia, which mediate the activity of key developmental signaling pathways. Through whole exome...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Tian, Hua, Feng, Jifan, Li, Jingyuan, Ho, Thach-Vu, Yuan, Yuan, Liu, Yang, Brindopke, Frederick, Figueiredo, Jane C., Magee, William, Sanchez-Lara, Pedro A., Chai, Yang
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6075526/
https://ncbi.nlm.nih.gov/pubmed/28069795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddx002
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