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IGF1 neuronal response in the absence of MECP2 is dependent on TRalpha 3

Rett syndrome (RTT) is an X-linked neurodevelopmental disorder in which the MECP2 (methyl CpG-binding protein 2) gene is mutated. Recent studies showed that RTT-derived neurons have many cellular deficits when compared to control, such as: less synapses, lower dendritic arborization and reduced spin...

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Bibliografske podrobnosti
izdano v:Hum Mol Genet
Main Authors: de Souza, Janaina S., Carromeu, Cassiano, Torres, Laila B., Araujo, Bruno H. S., Cugola, Fernanda R., Maciel, Rui M.B., Muotri, Alysson R., Giannocco, Gisele
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6075524/
https://ncbi.nlm.nih.gov/pubmed/28007906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw384
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