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Organic Anion Transporting Polypeptides Contribute to the Disposition of Perfluoroalkyl Acids in Humans and Rats

Perfluoroalkyl sulfonates (PFSAs) such as perfluorohexane sulfonate (PFHxS) and perfluorooctane sulfonate (PFOS) have very long serum elimination half-lives in humans, and preferentially distribute to serum and liver. The enterohepatic circulation of PFHxS and PFOS likely contributes to their extend...

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Bibliografiske detaljer
Udgivet i:Toxicol Sci
Main Authors: Zhao, Wen, Zitzow, Jeremiah D., Weaver, Yi, Ehresman, David J., Chang, Shu-Ching, Butenhoff, John L., Hagenbuch, Bruno
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6075085/
https://ncbi.nlm.nih.gov/pubmed/28013215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfw236
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