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Organic Anion Transporting Polypeptides Contribute to the Disposition of Perfluoroalkyl Acids in Humans and Rats

Perfluoroalkyl sulfonates (PFSAs) such as perfluorohexane sulfonate (PFHxS) and perfluorooctane sulfonate (PFOS) have very long serum elimination half-lives in humans, and preferentially distribute to serum and liver. The enterohepatic circulation of PFHxS and PFOS likely contributes to their extend...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Zhao, Wen, Zitzow, Jeremiah D., Weaver, Yi, Ehresman, David J., Chang, Shu-Ching, Butenhoff, John L., Hagenbuch, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6075085/
https://ncbi.nlm.nih.gov/pubmed/28013215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfw236
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