Autotaxin–Lysophosphatidic Acid Signaling in Alzheimer’s Disease

The brain contains various forms of lipids that are important for maintaining its structural integrity and regulating various signaling cascades. Autotaxin (ATX) is an ecto-nucleotide pyrophosphatase/phosphodiesterase-2 enzyme that hydrolyzes extracellular lysophospholipids into the lipid mediator l...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Ramesh, Sindhu, Govindarajulu, Manoj, Suppiramaniam, Vishnu, Moore, Timothy, Dhanasekaran, Muralikrishnan
Format: Artigo
Language:Inglês
Published: MDPI 2018
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6073975/
https://ncbi.nlm.nih.gov/pubmed/29933579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19071827
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