Mechanisms of Tumor Growth Inhibition by Depletion of γ-Glutamylcyclotransferase (GGCT): A Novel Molecular Target for Anticancer Therapy

γ-Glutamylcyclotransferase (GGCT), which is one of the major enzymes involved in glutathione metabolism, is upregulated in a wide range of cancers—glioma, breast, lung, esophageal, gastric, colorectal, urinary bladder, prostate, cervical, ovarian cancers and osteosarcoma—and promotes cancer progress...

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Dades bibliogràfiques
Publicat a:Int J Mol Sci
Autors principals: Kageyama, Susumu, Ii, Hiromi, Taniguchi, Keiko, Kubota, Shigehisa, Yoshida, Tetsuya, Isono, Takahiro, Chano, Tokuhiro, Yoshiya, Taku, Ito, Kosei, Yoshiki, Tatsuhiro, Kawauchi, Akihiro, Nakata, Susumu
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2018
Matèries:
Review
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6073726/
https://ncbi.nlm.nih.gov/pubmed/30011933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19072054
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