Targeting the NLRP3 Inflammasome-Related Pathways via Tianeptine Treatment-Suppressed Microglia Polarization to the M1 Phenotype in Lipopolysaccharide-Stimulated Cultures

An increasing body of evidence postulates that microglia are the main mediators of inflammation-related disorders, including depression. Since activated microglia produce a wide range of pro- and anti-inflammatory factors, the modulation of M1/M2 microglial polarization by antidepressants may be cru...

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Publicat a:Int J Mol Sci
Autors principals: Ślusarczyk, Joanna, Trojan, Ewa, Głombik, Katarzyna, Piotrowska, Anna, Budziszewska, Bogusława, Kubera, Marta, Popiołek-Barczyk, Katarzyna, Lasoń, Władysław, Mika, Joanna, Basta-Kaim, Agnieszka
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6073715/
https://ncbi.nlm.nih.gov/pubmed/29976873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19071965
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