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Recent Trends and Applications of Molecular Modeling in GPCR–Ligand Recognition and Structure-Based Drug Design

G protein-coupled receptors represent the largest family of human membrane proteins and are modulated by a variety of drugs and endogenous ligands. Molecular modeling techniques, especially enhanced sampling methods, have provided significant insight into the mechanism of GPCR–ligand recognition. No...

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Bibliografski detalji
Izdano u:Int J Mol Sci
Glavni autori: Yuan, Xiaojing, Xu, Yechun
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6073596/
https://ncbi.nlm.nih.gov/pubmed/30036949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19072105
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