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Functional Characterization and Structure-Guided Mutational Analysis of the Transsulfuration Enzyme Cystathionine γ-Lyase from Toxoplasma gondii

Sulfur-containing amino acids play essential roles in many organisms. The protozoan parasite Toxoplasma gondii includes the genes for cystathionine β-synthase and cystathionine γ-lyase (TgCGL), as well as for cysteine synthase, which are crucial enzymes of the transsulfuration and de novo pathways f...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Maresi, Elena, Janson, Giacomo, Fruncillo, Silvia, Paiardini, Alessandro, Vallone, Rosario, Dominici, Paola, Astegno, Alessandra
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6073527/
https://ncbi.nlm.nih.gov/pubmed/30036991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19072111
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