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The Anti-Wrinkle Mechanism of Melatonin in UVB Treated HaCaT Keratinocytes and Hairless Mice via Inhibition of ROS and Sonic Hedgehog Mediated Inflammatory Proteins

Though melatonin is known to improve ultraviolet B (UVB)-induced oxidative damage and inflammatory conditions via the blockade of the nuclear factor (NF)-κB, interleukin (IL)-6, there is no report on the anti-wrinkle effect of melatonin to date. Hence in the present study, the anti-wrinkle mechanism...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Park, Eun Kyung, Lee, Hyo-Jung, Lee, Hyemin, Kim, Ju-Ha, Hwang, Jisung, Koo, Ja Il, Kim, Sung-Hoon
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6073225/
https://ncbi.nlm.nih.gov/pubmed/29986551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19071995
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