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Recent advances in prostate cancer research: large-scale genomic analyses reveal novel driver mutations and DNA repair defects

Prostate cancer (PCa) is a disease of mutated and misregulated genes. However, primary prostate tumors have relatively few mutations, and only three genes ( ERG, PTEN, and SPOP) are recurrently mutated in more than 10% of primary tumors. On the other hand, metastatic castration-resistant tumors have...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:F1000Res
Prif Awduron: Frank, Sander, Nelson, Peter, Vasioukhin, Valeri
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: F1000 Research Limited 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6073096/
https://ncbi.nlm.nih.gov/pubmed/30135717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.14499.1
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